Journalwatch: Trends in Neurosciences, June, 2011

Only one article to recommend. It’s not groundbreaking at the theoretical level, but consistent with the main focus of this site, works its way up to describing the neural circuit for predicting danger. We definitely can use these nice details and synthesis to improve our working understanding of how reward prediction error runs the nervous system. 

Gavan P. McNally,Joshua P. Johansen, Hugh T. Blair. Placing prediction into the fear circuit (Review). Trends in Neurosciences. Volume 34, Issue 6, June 2011, Pages 283-292

Abstract: Pavlovian fear conditioning depends on synaptic plasticity at amygdala neurons. Here, we review recent electrophysiological, molecular and behavioral evidence suggesting the existence of a distributed neural circuitry regulating amygdala synaptic plasticity during fear learning. This circuitry, which involves projections from the midbrain periaqueductal grayregion, can be linked to prediction error and expectation modulation of fear learning, as described by associative and computational learning models. It controls whether, and how much, fear learning occurs by signaling aversive events when they are unexpected. Functional neuroimaging and clinical studies indicate that this prediction circuit is recruited inhumans during fear learning and contributes to exposure-based treatments for clinical anxiety. This aversive prediction error circuit might represent a conserved mechanism for regulating fear learning in mammals.


  1. erin, these are exactly as i had in my head when we were shinootg. they turned out perfectly. i love love love the relaxed lifestyle sessions and this family were perfect models for it. baby d is a charmer. my favorite is the one of him with arms stretched out on his blanket ready to take on the world. my second favorite is the set of mom and dad on the couch with him asleep taken from the side and from above. those are so peaceful and colorful at the same time. a good balance of colors and calmness. lovely work! we need more of these types of models and sessions!lesli

  2. this is certainly a genuine as well as a amazing report and i genuinely value the efforts of paying your time for you to generate it to us to learn significantly more in this particular issue as well as to talk about the information and details about the involved matter.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s